Webinar
Organized by the ECNP Network Immuno-NeuroPsychiatry
Save the date: Monday, 14.00-17.00 hrs., December 9th 2024
Immuno-Psychiatry:
T cell pathogenesis and novel immune therapies for mood disorders.
The pathogenesis of mood disorders remains largely unexplained. The last three decades studies have identified several immune pathophysiological mechanisms and potential immune predictors of treatment outcome for mood disorders. The integration of all these data into a neuro-immune model starts to make it possible to identify homogeneous subgroups of patients, diagnosed by objective and quantifiable assays, which enables therapy strategies that are more effective than the regular ones because they are based on the correction of the underlying immune biological mechanisms.
Program:
14.00 Introduction into the basics of the T cell system (Hemmo Drexhage).
Chairs: Bernard Baune, Elisa Brietzke
14.15 Neuroimmunology and ageing (Roberto Paganelli, Moisés Bauer)
14.35 T cell senescence in major depressive disorder. Relation with low grade inflammation (Maria Simon)
14.55 Chronic CMV infection, T cell senescence and major depressive disorder (Jonathan Savitz)
14.15 Short interval
Chairs: Carmine Pariante, Paolo Brambilla
15.20 T cell differentiation abnormalities and low grade inflammation in bipolar disorder and children at risk for bipolar disorder (Benno Haarman)
15.40 Beneficial effects of low dose IL-2 therapy in unipolar and bipolar depression. The IL-2REG trial (Francesco Benedetti)
16.00 Beneficial effects of low dose IL-2 therapy in bipolar depression. The DEPIL trial (David Klatzman, Marion Leboyer)
16.20 Structured Round Table with chairs and speakers. Strategy on how to rapidly introduce T cell correction and anti-inflammatory therapies in psychiatric care. If you want to actively contribute with one slide to this topic, please notify h.drexhage@erasmusmc.nl.
